Can olanzapine cause thrombocytopenia?
Thrombocytopenia has rarely been reported to be associated with the use of olanzapine, and there are no exact data on the incidence of thrombocytopenia with the use of olanzapine.
Does olanzapine cause bone marrow suppression?
Of the adverse effects associated with olanzapine, bone marrow suppression is one of the most common, but spontaneous intracranial hemorrhage secondary to thrombocytopenia is rare. The present case report describes an 88-year-old man who presented with an intracranial hemorrhage after taking olanzapine for 2 weeks.
What is drug-induced thrombocytopenic purpura?
Drug-induced thrombocytopenic purpura is a skin condition result from a low platelet count due to drug-induced anti-platelet antibodies caused by drugs. Drug-induced thrombocytopenic purpura should be suspected when a patient, child or adult, has sudden, severe thrombocytopenia.
Can olanzapine cause pancytopenia?
Olanzapine-induced Pancytopenia: A Rare but Worrying Complication.
Does olanzapine cause leukopenia?
Doses ranged from 2.5 to 30 mg. After starting treatment, onset of hematotoxicity varied from the first day to 2–3 years, but most commonly within the first month. Also, olanzapine could induce leukopenia in patients who have never developed drug-related leukopenia.
Which antipsychotics cause bone marrow suppression?
Bone-marrow suppression is associated with first- and second-generation antipsychotics. Blood dyscrasia is a concern in clinical psychiatry because hematologic abnormalities can be life-threatening, requiring close monitoring of the blood count for patients taking an antipsychotic.
How do you identify drug-induced thrombocytopenia?
A low platelet count makes bleeding more likely. When medicines or drugs are the causes of a low platelet count, it is called drug-induced thrombocytopenia.
How is drug-induced thrombocytopenia diagnosed?
Laboratory Criteria for DITP The detection of drug-dependent platelet antibodies in vitro can confirm the diagnosis of DITP.
Does olanzapine cause neutropenia?
Olanzapine is an atypical antipsychotic with a low incidence of extrapyramidal-motoric side effects. Its chemical structure is related to clozapine, which is known to induce neutropenia in up to 3% and agranulocytosis in approximately 1% of patients.
Is there an association between olanzapine and thrombocytopenia?
In view of limited literature on the association of olanzapine and thrombocytopenia, we present a case of olanzapine-induced thrombocytopenia and review the existing literature. CASE REPORT Miss.
Can you take olanzapine with low platelet count?
In fact, it was never considered, despite the presence of low platelet count for 3 months. Thrombocytopenia has rarely been reported to be associated with the use of olanzapine, and there are no exact data on the incidence of thrombocytopenia with the use of olanzapine.
What is the prognosis of olanzapine-associated leucopaenia?
The prognosis of the patient was good and there was no relapse of any haematological abnormalities. In the index elderly subject, olanzapine-associated leucopaenia and thrombocytopaenia were detected just after 6 weeks of starting Olanzapine at a dosage of 15 mg/day.
Does olanzapine cause dysplastic cells?
Blood film did not reveal any evidence of any dysplastic cells, disturbance in the count of other cell lines, and autoimmune workup including antinuclear antibodies and anti-neutrophil cytoplasmic antibodies were found to be negative. Given no other etiology, olanzapine was gradually tapered, and platelet counts were monitored.