What is the difference between lupus and Lichen Planus?
Lichen planus (LP) is a chronic inflammatory mucocutaneous disorder with unknown etiology. Systemic lupus erythematosus (SLE) is known as a prototypic autoimmune disease. Cytokines play a key role in the pathogenesis of both diseases.
Can Sjogren’s be mistaken for lupus?
Overlapping symptoms The symptoms of Sjogren’s syndrome and lupus can be very similar. In some cases, it can be hard to tell the two apart. This may lead to the diagnosis of both conditions in a person who only has one or the misdiagnosis of someone who actually has both.
Can Sjogren’s cause Lichen Planus?
As a result, atrophic lesions of the mucosa are a common observation in cases of Sjogren’s syndrome and other salivary gland diseases. These epithelial changes can occur in both the skin and mucous membranes in cases of lichen planus. These data suggest that both diseases are also related in a pathological manner.
Is Lichen Planus a form of lupus?
Lupus erythematosus (LE) and lichen planus (LP) are two distinct and well established dermatoses which occasionally can occur as an overlap syndrome. Overlap syndrome is characterized by mixed clinical and histopathological features of both LE and LP.
What kind of autoimmune disease is Lichen Planus?
Lichen planus is a chronic, inflammatory, autoimmune disease that affects the skin, oral mucosa, genital mucosa, scalp, and nails. Lichen planus lesions are described using the six P’s (planar [flat-topped], purple, polygonal, pruritic, papules, plaques).
What autoimmune diseases are similar to lupus?
Common diseases that overlap with lupus
- Autoimmune thyroid disease.
- Celiac disease.
- Myasthenia gravis.
- Antiphospholipid syndrome.
- Rheumatoid arthritis.
- Polymyositis.
- Dermatomyositis.
- Scleroderma.
Is Oral Lichen Planus a symptom of lupus?
Lupus has been associated with a wide spectrum of oral mucosal lesions: cheilitis, erythematous patches, `honeycomb’ plaques, discoid lesions, lichen planus (LP)-like lesions and discrete ulcers (Figure 3) (Table 3). In established disease, reported prevalence rates range from 9% to 45% of cases.
What autoimmune causes lichen planus?
Lichen planus (LP) is thought to be an autoimmune disorder in patients with a genetic predisposition but may be caused by drugs or be associated with disorders such as hepatitis C. LP is characterized by recurrent, pruritic papules that are polygonal, flat-topped, and violaceous and can coalesce into plaques.
Is Lichen Planus a autoimmune disease?
Is Oral Lichen Planus an autoimmune disease?
Lichen planus (LP) is a rare, chronic, inflammatory autoimmune skin and mucous membrane disease. LP most commonly presents as itchy, shiny, reddish-purple spots (lesions) on the skin (cutaneous LP) or as white-gray lesions in the mouth or on the lips (oral LP).
Is lichen planus associated with lupus?
Lupus erythematosus lichen planus (LE-LP) overlap syndrome remains an uncommon diagnostic entity, combining both the histologic and clinical features of lupus erythematosus and lichen planus. A rare and challenging diagnosis, clinicopathologic correlation is essential for accurate and timely identification.