Can you have Factor 5 and factor 2?
Factor V and II are blood clotting proteins. Variations in these proteins may increase the risk of dangerous cardiovascular events caused by venous thrombosis. In clinical studies, it has been shown that several genetic defects are associated with increased risk of venous thrombosis.
What is a factor 5 deficiency?
Factor V deficiency is caused by a lack of factor V. When certain blood clotting factors are low or missing, your blood does not clot properly. Factor V deficiency is rare. It may be caused by: A defective factor V gene passed down through families (inherited)
Is Factor 5 an autoimmune disease?
Examples include abnormalities in Protein C, Protein S, Antithrombin, and Prothrombin 20210. Another disorder which leads to increased clotting is the Anti-Phospholipid Syndrome. This is an autoimmune disorder in which one’s own immune system attacks normal anti-clotting mechanisms.
Is Factor V Leiden life threatening?
Factor V Leiden can cause blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism). These blood clots can be life-threatening.
How is factor 2 treated?
Treatment of factor II deficiency is aimed at restoring circulating factor II to levels sufficient for hemostasis. Levels greater than 30% of normal are usually adequate. Treatment measures include fresh frozen plasma (FFP), prothrombin complex concentrates (PCCs), and vitamin K.
What causes factor 2 mutation?
You may inherit an abnormal Factor II gene from one or both parents. If you get the mutation from both of your parents, you are homozygous (you have two abnormal copies of the Factor II gene).
Does Factor 5 make you bleed more?
Factor V Leiden is a genetic blood disorder caused by a mutation in the gene that controls factor V, a main element in blood clotting. This mutation causes excessive bleeding and the development of blood clots.
How is factor V deficiency treated?
Factor V deficiency is treated with infusions of fresh frozen plasma (FFP) and blood platelets. These infusions are typically needed only after surgery or a bleeding episode.