What is papaverine phentolamine used for?
Papaverine is used to produce erections in some men with erectile dysfunction. When papaverine is injected into the penis (intracavernosal), it increases blood flow to the penis, which results in an erection.
What is the strongest Trimix available?
TriMix Dosage Increase by 0.025 cc to 0.050 cc until a satisfactory dose is reached. The maximum dose is 0.50 cc. Patients should not be discouraged by a poor result with the first few injections, as the initial dose should be kept low to avoid a prolonged erection.
What is alprostadil papaverine phentolamine?
Papaverine, phentolamine, and alprostadil (PGE1) are the drugs that have been used for intracavernous injection therapy. Papaverine is an inhibitor of PDE enzyme leading to increase cGMP in penile tissue.
How long does an erection last after injection?
Both these drugs have their effect by causing dilatation (widening) of the blood vessels to the penis. The erection usually starts between 5 to 10 minutes after the injection and the erection usually lasts between 1 and 2 hours.
What does prostaglandin E1 do?
Prostaglandin E1 (PGE1) is a medication used in the management of erectile dysfunction and ductus arteriosus in neonates. It is a smooth muscle relaxant and vasodilator.
Is there something better than Trimix?
QuadMix is usually more effective than comparable Trimix with the same volume and similar concentrations of component medications.
What is the side effect of phentolamine?
Common side effects of phentolamine include injection site pain, headache, and changes in heart rate. Phentolamine can also cause dizziness.
Is prostaglandin the same as alprostadil?
Prostaglandin E1 (PGE 1) is also known as alprostadil. It is most effective for treating erectile dysfunction by opening blood vessels to increase vascular blood flow.
What is the cost of papaverine plus phentolamine?
Papaverine plus Phentolamine. Prostaglandin causes pain, sometimes severe, in about 20% of the users. The cost of a bi-mix injection is about $1 plus 25 cents for the syringe. Compared with papaverine Papaverine plus phentolamine (bimix) may be more effective at increasing the proportion of men achieving full erections 20 minutes after injection…
What are the disadvantages of papaverine phentolamine and prostaglandin E1?
Comparison of a mixture of papaverine, phentolamine and prostaglandin E1 with other intracavernous injections this triple mixture has the disadvantage of causing fibrosis and priapism in susceptible patients. this triple mixture has the disadvantage of causing fibrosis and priapism in susceptible patients.
How do you take papaverine and phentolamine together?
Papaverine plus Phentolamine. Bi-mix is a mixture of 30 mg papaverine and 1 mg phentolamine. The injections takes about 5 minutes, about 1 minute to clean with an alcohol swab and inject and another 3-4 minutes of holding pressure on the injection site after removing the needle. Most men will have a full erection within 5-15 minutes of injecting.
How much does it cost to mix papaverine and prostaglandin?
Papaverine plus Phentolamine. If bi-mix is not successful, doctor may prescribes tri-mix with the third ingredient being prostaglandin (Caverject). Prostaglandin causes pain, sometimes severe, in about 20% of the users. The cost of a bi-mix injection is about $1 plus 25 cents for the syringe.