What are gametocytes in malaria?
Gametocytes are specialized sexual precursor cells that mediate the transmission of the malaria parasite from the mammalian host to the mosquito. Once these cells have gained maturity, they are picked up by an Anopheles mosquito during a blood meal.
What is Exflagellation in Plasmodium?
Medical Definition of exflagellation 1 : the casting off of cilia or flagella. 2 : the formation of microgametes in sporozoans (as the malaria parasite) by extrusion of nuclear material into peripheral processes resembling flagella.
Which are the gametocytes formed in Plasmodium?
A gametocyte in Plasmodium falciparum is a cell specializing in the transition between the human and the mosquito host. Gametocytes arise from erythrocytic asexual stages. The production of gametocytes directly from hepatic merozoites, which has been described in other species, does not occur in P.
What is the importance of gametocytes in Plasmodium falciparum?
Gametocytes are the sexual stage of malaria parasites. The generation of male and female gametes is necessary for transmission to the mosquito vector where sexual recombination and generation of new haploid progeny takes place.
What do you mean by gametocytes?
Definition of gametocyte : a cell (as of a protozoan causing malaria) that divides to produce gametes.
What does Exflagellation mean?
n. the formation and release of mature flagellated male sex cells (see microgamete) by the microgametocytes of the malarial parasite (see Plasmodium). The process, which is completed in 10–15 minutes, occurs after the microgametocytes have been transferred from a human to the stomach of a mosquito.
What induces Exflagellation?
The change in pH, pCO2, and temperature under in vitro conditions are the principle triggers initiating exflagellation. For exflagellation assays of P.
What is Exflagellation where does it takes place in the life cycle of Plasmodium?
In the life cycle of a malaria parasite, the exflagellation of microgametocytes occurs in the stomach of the Anopheles mosquito. The presence of other forms of the parasite and the fact that exflagellation can occur in peripheral blood in P vivax infection will help in arriving at the correct diagnosis.
Which parasitic form of the malarial protozoan produces gametocytes?
merozoites
Plasmodium gametocytes form mostly during each of the asexual erythrocytic cycles, whereas in some species such as the human parasite P. vivax and the rodent parasite Plasmodium yoelii gametocytes can also be derived from the merozoites emerging from the pre-erythrocytic schizonts [87,88].
Where will you look for gametes of malarial parasite?
When a female Anopheles mosquito bites an infected person, Plasmodium enters the mosquito’s body and undergoes further development. The parasites multiply within them to form sporozoites that are stored in their salivary glands.