Does Depakote cause fatty liver?
Drugs reported to cause fatty liver include total parenteral nutrition, methotrexate (Rheumatrex), griseofulvin (Grifulvin V), tamoxifen (Nolvadex), steroids, valproate (Depakote), and amiodarone (Cordarone). In certain situations, fatty liver alone can be life threatening.
What causes Chrissos of the liver?
The most common causes of cirrhosis of the liver are: Alcohol abuse (alcohol-related liver disease caused by long-term [chronic] use of alcohol). Chronic viral infections of the liver (hepatitis B and hepatitis C). Fatty liver associated with obesity and diabetes and not alcohol.
Can epilim cause liver problems?
liver disease (hepatic dysfunction) or severe hepatitis. a family history of hepatitis, especially when caused by medicines. Medicines used in the treatment of epilepsy, including Epilim may have adverse effects on the liver and the kidneys.
Is Depakote toxic to the liver?
Depakote-induced hepatotoxicity has been well established as an adverse effect, and periodic monitoring of drug level is often required. Depakote-induced hepatotoxicity mostly occurs at supratherapeutic drug level.
Is Depakote hard on the liver?
Depakote can cause liver failure. The drug label carries a boxed warning regarding liver failure, or hepatotoxicity. Doctors may perform a liver biopsy to detect liver damage. Hepatoxicity is an inflammation of the liver.
Does valproic acid affect the liver?
Valproic acid may cause serious or life-threatening damage to the liver that is most likely to occur within the first 6 months of therapy.
Can Depakote cause cirrhosis of the liver?
A: The following serious side effects are associated with Depakote: Serious liver damage that can cause death, especially in children younger than 2 years old. Risk of serious liver damage is more likely to occur within the first 6 months of treatment, and may continue despite discontinued use of the drug.
How long can you live with a fatty liver?
Patients can live for many years with NAFLD, but many – about 30% – eventually end up with an inflamed liver or NASH (non-alcoholic steatohepatitis), and scarring. Of these, about 20% will develop end-stage cirrhosis, which can lead to liver failure and cancer.