Is Femara the same as letrozole?
Femara (generic name is letrozole) is an oral drug which can be an effective fertility treatment for women with ovulation problems, or for those with unexplained infertility. This medication is in a class of drug called aromatase inhibitors. Femara has mainly been used to treat certain cases of breast cancer.
Is letrozole generic for Femara?
Femara is the trade name for the generic drug letrozole. In some cases, health care professionals may use the trade name Femara ® when referring to the generic drug name letrozole. Drug Type: Letrozole is a hormone therapy.
Which is more effective letrozole or tamoxifen?
Background. The aromatase inhibitor letrozole is a more effective treatment for metastatic breast cancer and more effective in the neoadjuvant setting than tamoxifen. We compared letrozole with tamoxifen as adjuvant treatment for steroid-hormone-receptor–positive breast cancer in postmenopausal women.
How effective is letrozole for metastatic breast cancer?
Letrozole has an average rating of 6.9 out of 10 from a total of 24 ratings for the treatment of Breast Cancer, Metastatic. 58% of reviewers reported a positive effect, while 25% reported a negative effect.
Is it better to take Femara in the morning or at night?
You can take letrozole at whatever time of day you find easiest to remember, but try to take your doses at the same time of day each day. This will help you to remember to take letrozole regularly. Swallow the tablet with a drink of water. You can take letrozole either with or without food.
Is Femara better than generic letrozole?
Does the more expensive brand-name drug Femara work better than generic letrozole? No. A generic medication is an exact copy of the active drug in a brand-name medication. Letrozole is the active drug in the brand-name medication Femara.
Is letrozole an immunosuppressant drug?
siponimod and letrozole both increase immunosuppressive effects; risk of infection. Use Caution/Monitor. Caution if coadministered because of additive immunosuppressive effects during such therapy and in the weeks following administration.
How long does it take for letrozole to shrink tumors?
Sixty percent of women taking letrozole showed tumor shrinkage after four months on the drug, whereas 41 percent of women taking tamoxifen showed tumor shrinkage. Patients taking letrozole also underwent fewer mastectomies (complete breast removal) than women who were taking tamoxifen.
Can Stage 4 breast cancer go into remission?
A partial response or partial remission means the cancer partly responded to the treatment somewhat, but it wasn’t completely destroyed. There’s still room for hope. Continued improvements in chemotherapy and other breast cancer treatments have led to improved survival rates for people with stage 4 cancer.
Who is the manufacturer of letrozole (Femara)?
Novartis, the manufacturer of letrozole (Femara), distributed the study drugs, provided financial support, and imposed no restrictions on the investigators with respect to trial data. The IBCSG Statistical Center had unblinded access to the database, and the IBCSG Data Management center had blinded access to the database.
Is letrozole safe for women with endocrine-responsive breast cancer?
Women given letrozole had a higher incidence of skeletal and cardiac events and of hypercholesterolemia. In postmenopausal women with endocrine-responsive breast cancer, adjuvant treatment with letrozole, as compared with tamoxifen, reduced the risk of recurrent disease, especially at distant sites. (ClinicalTrials.gov number, NCT00004205 .)
How many women were enrolled in the letrozole and tamoxifen trials?
A total of 8010 women with data that could be assessed were enrolled, 4003 in the letrozole group and 4007 in the tamoxifen group.
How much does letrozole inhibit aromatase activity?
With daily oral administration, anastrozole and exemestane inhibit aromatase activity in vivo by 97 to 98 percent and letrozole inhibits aromatase by more than 99 percent. 4-7