What is the structural formula of p-nitroaniline?
C6H6N2O2
4-Nitroaniline/Formula
What is the state of p-nitroaniline?
146 to 149 °C (295 to 300 °F; 419 to 422 K) (lit.) Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). 4-Nitroaniline, p-nitroaniline or 1-amino-4-nitrobenzene is an organic compound with the formula C6H6N2O2.
What is the pKb value of 4-nitroaniline?
12.99
4-Nitroaniline
| Properties. | |
|---|---|
| Formula | C6H6N2O2 |
| Refractive index | 1.5401 (160 C) |
| pKa/pKb | 12.99 (pKb) |
| Partition coefficient, pKow | 1.39 |
What is the nominal mass of p-nitroaniline?
138.042927438
3.1Computed Properties
| Property Name | Property Value |
|---|---|
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 138.042927438 |
| Monoisotopic Mass | 138.042927438 |
How do you convert aniline to p-nitroaniline?
Nitration: Direct nitration of aniline yields (p-nitroaniline) a mixture of ortho, meta, and para nitroanilines. In an acidic medium the -NH2 group is protonated to the -N+H3 group which is meta-directing and deactivating. Hence, a considerable amount of m-nitroaniline is obtained.
How will you prepare p-nitroaniline from aniline?
Dissolve 4.0 mL of aniline in 10 mL of acetic acid in a 100 mL round bottom flask. To this solution, add 5 mL of acetic anhydride and mix well by swirling. CAUTION: the reaction is exothermic and the flask becomes warm.
Is p-nitroaniline a base?
The first of these is the hybridization of the nitrogen. Secondly, aniline and p-nitroaniline (first two green shaded structures) are weaker bases due to delocalization of the nitrogen non-bonding electron pair into the aromatic ring (and the nitro substituent).
Is p-nitroaniline soluble?
Insoluble in water. This chemical is sensitive to moisture. Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fire.
How do you convert aniline to Meta nitroaniline?
Answer: Aniline when treated with acetoacetate will produce Nacetyl aniline. This if treated with H2SO4/HNO2/CH3COOH will produce paranito nacetyl aniline, which on hydrolysis will give para nito aniline. a bit of ortho form will also form but it will be very little and can be easily separated by distillation.
How is p-nitroaniline obtained from aniline as major product?
Nitration: Direct nitration of aniline yields (p-nitroaniline) a mixture of ortho, meta, and para nitroanilines. Preparation of p-nitroaniline: However, to get p-nitroaniline as a major product, the –NH2 group is first protected by acetylation and then nitration is carried followed by hydrolysis amide.
How do you convert aniline to p dinitrobenzene?
The following steps are involved in this conversion :
- Step 1 : Nitration of aniline. When the benzenamine or aniline react with the nitrous acid and sulfuric acid, the result is the formation of para-nitroaniline.
- Step 2 : Formation of diazonium salt.
- Step 3 : Formation of 1,4-dinitrobenzene.
How do you separate p-nitroacetanilide?
Large crystals of p-nitroacetanilide is obtained. Filter the crystals through filter paper. The separated p-nitroacetanilide is washed with cold water in order to remove excess of acid. It is crystallized from ethyl alcohol.
What is p-nitroaniline used for?
P-nitroaniline is a chromogenic molecule that is used as a dyestuff intermediate in industrial applications. In biochemical research, enzyme assays utilize modified aminoacyl or peptidyl p-nitroanilines as substrates.
What is the name of the compound with the formula 4-nitroaniline?
4-Nitroaniline. 4-Nitroaniline, p-nitroaniline or 1-amino-4-nitrobenzene is an organic compound with the formula C 6 H 6 N 2 O 2. It is an organic chemical compound, consisting of a benzene ring in which an amino group is para to a nitro group. This chemical is commonly used as an intermediate in the synthesis of dyes, antioxidants,…
What is nitroaniline made of?
4-Nitroaniline. It is an organic chemical compound, consisting of a benzene ring in which an amino group is para to a nitro group. This chemical is commonly used as an intermediate in the synthesis of dyes, antioxidants, pharmaceuticals, and gasoline, in gum inhibitors, poultry medicines, and as a corrosion inhibitor.
How do you synthesize 4-nitroaniline from aniline?
Below is a laboratory synthesis of 4-nitroaniline from aniline. The key step in this reaction sequence is an electrophilic aromatic substitution to install the nitro group para to the amino group. The amino group can be easily protonated and become a meta director. Therefore, a protection of the acetyl group is required.