Is 80 mg of pravastatin too much?
Adult Patients. The recommended starting dose is 40 mg once daily. If a daily dose of 40 mg does not achieve desired cholesterol levels, 80 mg once daily is recommended. PRAVACHOL can be administered orally as a single dose at any time of the day, with or without food.
Is there a black box warning for statins?
Background: In 2012, the U.S. Food and Drug Administration (FDA) mandated black box warnings for all statin drugs for possible adverse effects on cognitive performance including memory loss, amnesia, and confusion.
Is there a lawsuit against pravastatin?
An antitrust lawsuit has been filed against drug makers Actavis, Mylan, Teva and others, alleging they conspired to fix the price of the generic cholesterol medication pravastatin sodium.
What are the side effects of pravastatin 80 mg?
Common side effects of Pravachol include headache, nausea, vomiting, diarrhea, muscle pain, skin rash, dizziness, and abnormal liver tests.
Is Lipitor black box warning?
The FDA has rejected calls for a new black box warning for Lipitor, Crestor and other statin-based medications, which consumer advocates have called for to ensure information about the risk of severe and potentially life-threatening muscle problems and kidney damage is placed more prominently on the drug labels.
What drug companies make statins?
Statins: the drug firms’ goldmine
- Amongst the main players in the market include Pfizer, the world’s biggest drugs company; US-based Merck; and Britain’s second-biggest drug company, AstraZeneca.
- Pfizer’s Lipitor was the world’s top-selling medicine last year, according to IMS, raking in sales of $13.3billion.
Is 80 mg simvastatin safe?
[06-08-2011] The U.S. Food and Drug Administration (FDA) is recommending limiting the use of the highest approved dose of the cholesterol-lowering medication, simvastatin (80 mg) because of increased risk of muscle damage.
When should atorvastatin 80 mg be taken?
Take atorvastatin once a day. You can choose to take it at any time, as long as you stick to the same time every day. Sometimes doctors may recommend taking it in the evening. This is because your body makes most cholesterol at night.
Why to take pravastatin?
Pravastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.
How safe is pravastatin?
Pravastatin seems to be a very safe medicine. It’s unusual to have any side effects.