What does it mean when thyroid peroxidase is high?

What does it mean when thyroid peroxidase is high?

The presence of TPO antibodies in your blood suggests that the cause of thyroid disease is an autoimmune disorder, such as Hashimoto’s disease or Graves’ disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue.

What is a microsomal TPO antibody test?

A TPO test detects antibodies against TPO in the blood. Antithyroid microsomal antibody is a test to measure antithyroid microsomal antibodies in the blood. Microsomes are found inside thyroid cells. The body produces antibodies to microsomes when there has been damage to thyroid cells.

What happens if microsomal antibody is high?

A positive result may mean that you have a higher chance of developing thyroid disease in the future. This is often associated with a family history of thyroid disease. Antithyroid microsomal antibodies may be seen in your blood if you have other autoimmune conditions, including: Autoimmune hemolytic anemia.

How do I lower my TPO antibodies?

Selenium. Studies show that taking 200 mcg of selenium per day may help reduce antithyroid peroxidase (TPO) antibodies and improve well-being in people with Hashimoto’s disease ( 25 , 26 ). Zinc. Zinc is essential for thyroid function.

How can I lower my TPO antibodies naturally?

Beneficial supplements include:

1. Selenium. Studies show that taking 200 mcg of selenium per day may help reduce antithyroid peroxidase (TPO) antibodies and improve well-being in people with Hashimoto’s disease ( 25 , 26 ).
2. Zinc.
3. Curcumin.
4. Vitamin D.
5. B complex vitamins.
6. Magnesium.
7. Iron.

What is a TPO antibody test?

Thyroid peroxidase (TPO) is an enzyme normally found in the thyroid gland. TPO plays an important role in the production of thyroid hormones. A TPO test detects antibodies against TPO in the blood. If you’ve been diagnosed with thyroid disease, your doctor may suggest a TPO antibody test and other thyroid tests to help find the cause.

What are the possible complications of thyroid peroxidase (TPO) antibodies?

Some people with TPO antibodies may not have thyroid disease. However, the presence of TPO antibodies may increase the risk of future thyroid disorders. If you have normal thyroid function with TPO antibodies, your doctor may recommend periodic checkups to watch for future thyroid problems. Chernecky CC, et al., eds. Thyroid Peroxidase Antibody.

Is the anti-TPO assay for Thyroid microsomal fraction diagnostic valid?

The identification of the thyroid peroxidase (TPO) as the main antigen of the thyroid microsomal fraction has enabled the development of a sensitive and specific assay for detection of the corresponding autoantibodies. We evaluated the diagnostic validity of the anti-TPO assay in 303 patients with different types of thyroid disease and in controls.

Are anti-TPO antibodies linked to Graves’ disease?

According to the research, anti-TPO antibodies are detected in 90 to 95% of those with autoimmune thyroid conditions, including 80% in those who have Graves’ disease (3) .