Is minoxidil safer than Propecia?
Conclusion: In this comparative study of systemic finasteride and topical minoxidil, it was concluded that both drugs were effective and safe in the treatment of mild to severe AGA, although oral finasteride treatment was more effective (p < 0.05).
How do you treat non scarring alopecia?
For each type of non-scarring alopecia, a different therapeutic regimen is proposed, ie, telogen effluvium and trichotillomania are treated by removing the precipitating cause; anagen effluvium has no effective pharmacologic treatment, although topical minoxidil may help during the regrowth process; alopecia areata can …
Does minoxidil cause telogen effluvium?
Minoxidil acts by shortening the telogen phase, causing the quiescent hair follicles to enter prematurely into the anagen phase. The shortening of the telogen phase may induce telogen effluvium after the initiation of minoxidil therapy.
How much minoxidil is absorbed systemically?
Systemic absorption of minoxidil from topically applied solution ranges between 1% and 2% of the total applied dose. The systemic absorption of minoxidil from a 5 % foam formulation has been estimated in a pharmacokinetic study in subjects with androgenetic alopecia, which included 5 % topical solution as a comparator.
Can hair grow back from non-scarring alopecia?
With non-scarring alopecia, the hair follicle generally remains intact, however the hair shaft is either not produced, not produced correctly, or the follicle itself is miniaturized. With this type of alopecia, regrowth of hair is theoretically possible, although at times it is not able to be achieved.
What does non-scarring alopecia look like?
Alopecia areata is a type of non-scarring hair loss that can affect men and women, adults and children. The hair is usually lost in round or oval patches initially. This lost hair usually grows back without any other problems or any further hair loss.
Can minoxidil make hair loss worse?
Because minoxidil causes your hairs to prematurely enter into the anagen phase of the growth cycle, it may cause your hair to look worse before it looks better. By this, we mean that you might notice that your hair loss increases during the first few weeks or months of treatment with minoxidil.
Does minoxidil absorb into bloodstream?
Systemic absorption of topical minoxidil is less than 99% of the amount applied on the scalp. Minoxidil does not bind to plasma proteins or crosses the blood–brain barrier. Approximately 95% of the systemically absorbed drug and its metabolites are excreted via the kidney within 4 days.
How quickly is minoxidil absorbed?
Relative to the amount absorbed after a contact time of 11.5 h, absorption was approximately 50% complete by 1 h and greater than 75% complete by 4 h. This suggests that minoxidil absorption from the vehicle into skin occurs rapidly relative to diffusion through skin.
Does minoxidil enter your bloodstream?
Although the risk of serious side effects is low when minoxidil topical is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream.