What does the Barnes maze test?
The Barnes maze is a tool used in psychological laboratory experiments to measure spatial learning and memory. The test was first developed by Dr. This task is dependent on the intrinsic inclination of the subjects to escape from an aversive environment and on hippocampal-dependent spatial reference memory.
How does Barnes maze work?
The Barnes maze is a dry land task that also measures spatial memory. In this task, animals escape from a brightly lit open arena into a small recessed chamber located under the arena. Animals learn to navigate toward this target escape box by using spatial cues (Barnes, 1979).
How might you study working memory in rats trained in the water maze?
Probe trials to test memory Typically, a well-trained rat will swim to the target quadrant of the pool and repeatedly across the former location of the platform until starting to search elsewhere ( Figure 2C). This spatial bias, measured in various ways, constitutes evidence for spatial memory.
What does the T maze measure?
T Maze Spontaneous Alternation is a behavioral test for measuring exploratory behavior in animals, especially rodent models for CNS disorders. This test is based on the willingness of rodents to explore a new environment, i.e. they prefer to visit a new arm of the maze rather than a familiar arm.
What is Y maze?
Y Maze Spontaneous Alternation is a behavioral test for measuring the willingness of rodents to explore new environments. Testing occurs in a Y-shaped maze with three white, opaque plastic arms at a 120° angle from each other.
Is the Morris water maze stressful?
The effects of abnormally high or low stress on learning are well established. The Barnes maze and Morris water maze are two commonly-used tests of spatial memory, of which the water maze is considered more stressful; however, until now this has not been demonstrated empirically.
What is a major advantage of Aplysia for studies on the physiology of learning?
What is a major advantage of Aplysia for studies on the physiology of learning? there is great similarity of nervous system anatomy from one individual to another.
How do you use T-maze?
The basis behind the T-maze is to place the rat at the base of the maze. By placing a reward at one arm or both arms of the maze, the rat must make the choice of which path to take. The decision made by the rat can be a cause of a natural preference within the rat.
How does elevated plus maze work?
This test is designed to observe anxiety effects and how it affects learning. The rodent is placed on the enclosed arm and allowed to explore. The trial ends when the rodents sets all four paws in on the open arms. Rodents are allowed multiple trials until they learn to stay in the open arm for 300 seconds.
What is escape latency in Morris water maze?
One of the most commonly used performance measures is the escape latency, defined as the time for the animal to find the platform and escape the maze. Dalm et al.10, showed that the cumulative distance to the platform is correlated with the time spent next to the platform, but not with the escape latency.