What is cancer cell Line Encyclopedia?
The Cancer Cell Line Encyclopedia is a database of gene expression, genotype, and drug sensitivity data for human cancer cell lines. Citation(s) Barretina, J et al. (2012) The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
What is CCLE dataset?
The CCLE provides public access to genomic data, visualization and analysis for over 1100 cancer cell lines. This dataset contains RNA-Seq Aligned Reads, WXS Aligned Reads, and WGS Aligned Reads data.
Why do we use cancer cell lines?
Cancer cells that keep dividing and growing over time, under certain conditions in a laboratory. Cancer cell lines are used in research to study the biology of cancer and to test cancer treatments.
What is GEPIA2?
GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis.
How is a cell line made?
In order to get embryonic stem cell lines, scientists remove cells from the inner cell mass region. Once the cells are removed, they are placed on a culture plate with nutrients and growth factors. The blastocyst is destroyed in this process. An embryonic cell line is established when these cells multiply and divide.
Why are cell lines used?
Cell lines have revolutionized scientific research and are being used in vaccine production, testing drug metabolism and cytotoxicity, antibody production, study of gene function, generation of artificial tissues (e.g., artificial skin) and synthesis of biological compounds e.g., therapeutic proteins.
How do you use CCLE?
Getting Started
- Logging in. Your course website is located at http://ccle.ucla.edu.
- Find your course website. After logging in, you will need to find your course website.
- Start editing your course website.
- Change the layout of your course.
- Upload a file.
- Add a link.
- Add text and images onto a section page.
How is a cell line created?
Why are cell lines useful to scientists?
How many cancer cell lines are there?
Introduction to NCI-60 Human Cancer Cell Lines The 60 created cell lines represent nine human cancers: breast, central nervous system, colon, kidney, leukemia, lung, melanoma, ovary, and prostate.